Research Studies Currently Enrolling

JACK FARR, II, MD

Articular Cartilage Studies

Confirmatory Study of NeoCart in Knee Cartilage Repair\
Randomized trial comparing NeoCart, an implant of cartilaginous tissue derived from the patient’s own cells, to microfracture, a method of creating holes at the base of the cartilage defect bed to encourage growth of tissue within the defect.
www.neocartimplant.com
www.clinicaltrials.gov./ct2/show/NCT01066702

Mechanical Debridement vs. Radiofrequency-based Debridement to Treat Articular Cartilage Lesions with Partial Meniscectomy in the Knee.
Randomized trial comparing clinical and imaging outcomes following arthroscopic treatment of a single articular cartilage lesion and a partial medial meniscectomy (removal) by radiofrequency-based debridement or mechanical debridement.
www.clinicaltrials.gov/ct2/show/NCT1803880

Evaluation of the ReNu Amniotic Suspension Allograft after Marrow Stimulation in the Treatment of Osteochondral Defects
Pilot study evaluating the use of ReNu allograft for the augmentation of marrow stimulation (microfracture) for articular cartilage lesions.
www.clinicaltrials.gov/ct2/show/NCT03036878

Cartiform Prospective Study
Prospective registry study tracking outcomes of Cartiform articular cartilage implant for articular cartilage lesions of the patella (kneecap) and trochlea (portion of upper leg bone that articulates with patella)

Exactech Revielle PS Instrument Study
Prospective registry study tracking outcomes of articular cartilage defects treating with the Reveille cartilage processing instrument.

Meniscal Studies

Verifying the Effectiveness of the NUsurface System (VENUS Meniscal Study)
Randomized trial comparing conservative (non-operative) treatment to artificial meniscus implant inserted through a small incision.
www.meniscus-trial.com

Study of Suture Repair of Torn Meniscus in the Knee (STITCH Study)
Prospective, non-randomized study assessing various horizontal meniscus tear repair techniques.
www.clinicaltrials.gov/ct2/show/NCT02237001

Osteoarthritis/Bone Studies

Prospective, Multi-Center, Single Arm, Pilot Study to Evaluate Symptom Relief in Subjects with Medial Knee Osteoarthritis Treated with the AtlasTM Knee System for Load Reduction
Pilot study to collect data on the safety and effectiveness of the AtlasTM Knee System, an implanted system designed to treat knee OA by absorbing excess load.
www.atlaskneestudy.com
www.clinicaltrials.gov/ct2/show/NCT02934659

Saline-Controlled Study of nSTRIDE® APS for Knee Osteoarthritis
Randomized trial comparing nSTRIDE® APS knee injection, an autologous protein solution prepared with a sample of a patient’s own blood using the investigational nSTRIDE® APS Kit and injected into the knee joint, to a saline injection.
www.zimmerbiomet.com/nSTRIDEtrial
www.clinicaltrials.gov/ct2/show/NCT02905240

Subchondroplasty® Observational Cohort Follow-Up Study
Registry study tracking outcomes of stress fractures/subchondral bone defects treated with AccuFill® Bone Substitute Material.

Other Studies

Justifying Pediatric Instability Treatment by Early Results (JUPITER) Study
Prospective cohort study comparing (1) non-operative treatment, (2) isolated medial patellofemoral ligament (MPFL) reconstruction, and (3) “a la carte” surgical approach to treat patellar instability.

 

DAVID FISHER, MD

OUTCOMES OF TOTAL KNEE ARTHROPLASTY (TKA) USING THE ATTUNE® CEMENTLESS PRIMARY ROTATING PLATFORM TOTAL KNEE SYSTEM
The objective is to provide early post-market data on the DePuy Synthes ATTUNE® Cementless Rotating Platform (RP) Knee. Effectiveness will be evaluated using clinical outcome scoring and radiographic evaluation. Patients will be seen post-operatively at 6 weeks and 1 year.

 

FRANK KOLISEK, MD

A post market multi-center study of the application and workflow of robotic-arm assisted total knee arthroplasty.
This study examines the efficiency and workflow of using a robotic arm to assist with total knee replacements.

 

SANFORD KUNKEL, MD

A post-market observational study to evaluate performance and safety of the TITAN total shoulder system.  Patients that previously had a shoulder replacement using the TITAN system can enroll in this long-term follow-up study.

 

MEREDITH LANGHORST, MD

ReActive8 implantable neurostimulation system for chronic low back pain. The purpose of this study is to show whether the ReActiv8®, is safe and effective to reduce chronic low back pain when medication and physical therapy are not working. If you have chronic low back pain and are not a candidate for surgery, please click the link below for more information. Co-investigator Dr. David Schwartz.
https://clinicaltrials.gov/ct2/show/NCT02577354?term=NCT02577354&rank=1

 

GREGORY POULTER, MD

Evaluation of spine fusion using Vesuvius demineralized fibers with the Everest Spinal System. The purpose of this study is to collect data on how you are doing from the spine surgery you are having which utilizes the K2M EVEREST® Spinal System using bone graft extender such as the VESUVIUS™ Demineralized Fibers. If you have low back or leg pain and have not had surgery, please click the link below to find out more information on this study.
https://clinicaltrials.gov/ct2/show/NCT02064855?term=NCT02064855&rank=1

 

ORTHOINDY TRAUMA TEAM

FIXIT study: comparing 2 different treatments for severe open tibia fractures.
https://clinicaltrials.gov/ct2/show/NCT01494519?term=FIXIT&rank=1
PI: Crichlow, co-investigators: all trauma

Quality of Life & Prosthetic Use in the Above Knee Amputee
PI: Kaehr